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Staff Software Engineer

David Joseph & Company

HybridSan Francisco, CAlead$210kโ€“$260kPosted 1h ago

Visa & sponsorship

  • Accepts H-1B transfers (you must already hold H-1B status) but will not file new petitions.

Job description

Staff Software Engineer

Our client is a seed-stage healthcare/life-sciences company building AI agents that automate clinical trial workflows โ€” attacking one of the biggest bottlenecks in drug development. Backed by $7M+ in funding, the platform is already used across 400+ research sites. This is a founding tech-lead role on a small, high-impact engineering team.

The role: A hands-on Staff Software Engineer (8+ yrs) to be the technical anchor of a small team โ€” writing and reviewing code daily while mentoring three junior engineers and establishing engineering best practices, and partnering with product, customer success, and founders to ship zero-to-one AI-powered products.

Responsibilities

  • Own and build AI-powered products end-to-end (agentic workflows, LLM features with production evals)

  • Technical lead and mentor for three junior engineers; set best practices for code review and process

  • Partner with CTO, PM, and customer success to shape zero-to-one products

  • Architect and deliver full-stack apps across frontend, backend, infra, and data pipelines

Must-have

  • Tech lead / technical anchor experience on an engineering team

  • Full-stack product engineer who owns features end-to-end (backend-leaning generalists welcome)

  • Mentor / bar-raiser able to establish engineering best practices

  • 8โ€“15 yrs full-stack product engineering, building AI/LLM features

  • Zero-to-one, customer-facing product background (not deep infra)

  • Recent (1โ€“2 yrs) hands-on shipping of LLM features / AI agents in production

Nice-to-have

  • Mix of startup (seedโ€“Series B, founding/early hire) and larger-company experience

  • CS degree or equivalent

  • Production AI evals / LLM observability (LangSmith, Braintrust, W&B); multi-step agentic pipelines

  • Genuine interest in bio, life sciences, or healthcare

Compensation & logistics

  • Base salary: $210Kโ€“$260K, flexible for exceptional candidates

  • Equity: 1โ€“1.5%

  • Full-time, hybrid: 3 days/week in-office (Mon, Tue, Thu), Financial District, San Francisco

  • Visa: open to transfers (e.g., OPT, H-1B transfers); no new sponsorships

  • Interview process: 3 steps โ€” 30-min intro call, virtual system design interview, final on-site (technical + behavioral + team lunch)